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Synthetic Control Arm® in Clinical Trials


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A Synthetic Control Arm® is a type of external control that is generated using external patient-level data to improve the interpretation of uncontrolled trials. They can help enhance the scientific validity of single-arm trials; in certain indications, and can reduce time and costs associated with trials, and expose fewer patients to placebos or existing standard-of-care treatments that might not be effective for them.

See how a Synthetic Control Arm® can benefit your trials, including:

- Defining a Synthetic Control Arm®
- Components needed to build a Synthetic Control Arm®
- Benefits for patients and sponsors
- Case studies in non-small-cell lung cancer (NSCLC), multiple myeloma, and from Celsion Corporation