Blackberry revealed plans to lay off 40% of its workforce by the end of the year, as it prepares to launch its new Z30 smartphone.
The redundancies would affect nearly 5,000 employees, follows its slashing of another 5,000 jobs in 2012.
Blackberry said in a statement that the firm is undergoing the second phase of its transformation plan.
"Organisational moves will continue to occur to ensure we have the right people in the right roles to drive new opportunities in mobile computing," the smartphone maker said.
Unveiled in Malaysia, the new top-end device runs on the 10.2 operating system and the company hopes it will help claw back lost ground in the competitive global smartphone market.
Powered by a dual-core 1.7GHz Snapdragon S4 Pro processor, the new device boasts 5" Super AMOLED touchscreen, 2,880mAh battery, 2GB of RAM, 8MP rear camera and 2MP front-facing camera.
The new smartphone also incorporates latest antenna technology, which is targeted at dynamically tuning reception to boost user connectivity in low signal areas, while offering rapid data transfers and fewer dropped calls.
The Canadian smartphone maker is also planning to launch a BlackBerry Messenger (BBM) instant chatting app for rival iPhone and Android devices during the weekend.